Virtual Switching System now available on 4500 Series switches
The Catalyst 4500 switches now support VSS. If they have not already, I expect many campus engineers to start learning such terms as MEC, VSL, and relearning PagP(Yes, really).
http://www.cisco.com/en/US/docs/switches/lan/catalyst4500/15.1.2/XE_340/configuration/guide/OL_27597.pdf
It’s worth noting that WCCP and L2TP break when VSS is enabled.
This brings the 4500 to the level of Core capability in the campus. It kind of did anyway since the SUP-6 where it had higher throughput than the 6500 for a short time frame.
Right now Cisco Options I think one could consider for the core for a large campus (4 or more multi-floor buildings or at least 16 MDF and IDF closets) can be the Nexus 7000, the Catalyst 6500, or the Catalyst 4500 in order of price.
Vritual Virtual*